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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c1a0da9c6bae80cbf377e8e92f15987a7e0604ab45fb54beb5d80aa8f56556f' 
  AND token = '4c42/EIl9zYSM2M5tqJ9myhBAGhDWPd1IAn7Lf8MS6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}