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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3761d936615e10cb13aac3b67e24034e2d4a65da7ee3bd05a083f3397ddbcf7' 
  AND token = 'Tsk6y36ebmCG4zFDO8lzVl769+JnI56otqjrYg8Xx64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}