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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f77868e0a1c4b05f807432cbb2c25a2f7181cc3b779623b79b10e4af91bed65' 
  AND token = '8qCG7rXYeRuI3k0w6xIDxq45cqJQ4XaS5pjhppcWx+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}