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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85f81d05d6d2f0dd8ca9c1103da2ce59be4be510fa0778bcd9af90f85cc7b31c' 
  AND token = 'aPKaAQg3mgPIBlgihAzXqPbSyAn4eGjoBBa0hpGAsCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}