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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cb83daa2e63a4a19a1ed1067942c9c812948d90046a03ed0843b5096cdd5ed0' 
  AND token = 'kEsdcKwmWlw+bBFHNxYgK8NHoC2yO+vY+HJWVjag1yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}