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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66b46a089cafa9380c6170ab1ba7e2d81af2b1af6bb6a0fe95f1a6c175d253ca' 
  AND token = 'KExEir1q0FCQWma3QtA/IX3+2m2uhF4DiK9jDz22mQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}