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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff7ea60580cae2df4fa61a9e07d52e1a635e488af0aec241bc3700d90d9e0a8' 
  AND token = 'V3QWxKvvC3LgTJmv5F65Lfy1dC4/aT5JfX7rKcj4Z8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}