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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd89f4956f2b00d9a009ebea14f80ceff61cbc1809971ddc4ef30e80d5501d9e2' 
  AND token = 'S1cSr4XVjPTh3TShCgZk1XnrUPSNDI55B9ZY+AJiKvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}