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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a92fe8d12d374bca13ee44e979643e1b771b00916b2ff160343cd1b0b0b49b' 
  AND token = 'uJ/+bgYx0sfPtJwTVtSLVq9Y7EaCHvb7GYCiB0Y1l2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}