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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e437e02a59300471e4b52e4f1fc1aa6497673700030b107350d4c6c8f0a587d5' 
  AND token = 'hOS0TytY8COBknfruOzr5JiedTf/Gjb9qBo1NNk0ZAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}