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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd23289cc23ab224b1553750b1a32ccbc10ed47f0d08c77b5ab5384e04698804' 
  AND token = 'CGie/crAA3+pC7hvyZqaFX/y1WT6Ba6eMLkeaz+4GIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}