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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f6007eef99913a4fda221d7860e2bbf037f59c8724cff5ecdaed672b6c0482b' 
  AND token = '0y8V47QuV/IJwgfWllIpHmrOFPPfcOIRPmE78fi+Yks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}