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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b0489a30bd41d4d0f39f624ffdc52a413ed05476ac4d9c66b8094be3b384d5' 
  AND token = '77PmbsDPFLMRpkMTM9k2G+3vdlVb+ujWpXByh3Of2VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}