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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cb3074e07e8b5ae7358b2d38e2b69bb06ba8ec24490d4cf4465062a0fcb365' 
  AND token = '49dXK+tnltLWVFYFHRXVrYXkMOY0RvB78/d1fqceAxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}