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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd58b8c48d117bfd342c6d9f45bb2311e2c7abb120750c3f4063d2eeebc8e49f3' 
  AND token = '9Ub0P1R84fNS/246y27MB26NSmimZFzofRvTYuXj548=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}