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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad0f94c306d5e659c5ec515c23654d7d5bf99a6086bd997937c6ac2bd1949a2' 
  AND token = 'qQKr8KU0SZBFd07sPT0mS1dQRLjqFSvBqZoA7i7Sx44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}