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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d93cd4d2a5a84d78974ecb86666d48657074275d4463550d266c4ad3c22a560' 
  AND token = 'zkmDKN49BHeDN12J6ios/RWmzZdqC/posEq5G88ikmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}