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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd3c35df4bdd13269a7efd40e94b6a207dcc6de9c8516f136587e38b1eb031f' 
  AND token = 'LaQ4Kyz9LzyFjc0rnVXLwCmTdOP41C+gJtItMg3KXP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}