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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25ec104622b170a32319bc92c53119ccfc66020966ac0ca0eaf11588c069e05b' 
  AND token = 'OBIcL/H32Q69lm3/qAw2LmzxXq3RlpiSyMr11P1gD7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}