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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '725675f6a39a21b67a2a8ce20c586a8769631d461b3bf666b92746ed6f2fa152' 
  AND token = 'Gbk4Zj7LaeAckHkw6q9l5JW8o4x3zyQY0mDCSyLZTQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}