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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb3fe135c70e8e79bbea583f493a5c0d17b2eadd2171bee753f237f67a4d99c1' 
  AND token = 'Fl+32tkMCuMKjxdAjZZRxAIeJmZ6O9/E84w+HA4rkoc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}