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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10b746d6afd294f6c063e502c525784be44571a0f6fa182dbedb798adf997b32' 
  AND token = 'k2sIBv+0fhY08LxIR16kgdHy/TPO2Z2Jhukbj3ND37g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}