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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db2d2ed5da55e42971f61029a027ba56e745cf1988501b8802ace94d79312c55' 
  AND token = 'oqlWDNKwtp+15L8sGWFp9K60YWRqduWQFoZGErLC1MI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}