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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ac1b1e930790c62b75358914ddcb7bce21c747bc538637a5b3b3f586c65d82' 
  AND token = 'Hz3tgemm9912BbKGpbQMGViouwK92y8WujmmbdI+yQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}