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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3033c1e9fc7c194811fe6fa62a44b04c93ad92b53d5d31c162609e758c1e1f6' 
  AND token = 'ZQzQG9NirtmexVx0sZ0m2mhYk6/1dCtPKsm6mgktHKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}