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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0482293d8cb9d566ebb00c3931dd273eef92488fbf2dff96d1eec3c359a3fe12' 
  AND token = 'D7ITzGqFXfMtFf81plJCO1ruZyTkHRrWOjTZS8Qv2gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}