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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0180396ca1f55ec0e73ede0685db0e95c4fc2191fd15a665f88f71d1baa28a2' 
  AND token = 'uI/D45/wcJMpgVebf/OFBGFsOtHQnUcacS76o55Zcr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}