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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9442d4b1a9834b992595c5376d06639ba162a4eeafc3e5c6279a42fda4f11572' 
  AND token = 'Jqls480r+IGZuA1xY29vxisB4Z66NGdpmLz1d7fdn2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}