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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21d95d0438e0608de52a7a97a6559b9797ac463fe433658e52ed6123c2c682cc' 
  AND token = 'DCniEy6GVIUETma3X0HPtsE3WIbnWP6TUxlSwB8kjt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}