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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91cf5a84b8cc2c490cca03f4bcedd5c21bcfc4f58429f2d33a587967e0c4262e' 
  AND token = '1VipYXzptoEMD2JmNzPHLPRNXuiYO4hTPnhEw1iiD3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}