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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '125e97d2eb9fc813c7b4c3ee667ec82801e338ce0e817a18fd44f8d439131bef' 
  AND token = 'lzVnM/MDAPyQiwPj90jDmNqmGic1OeTvyTsXC10k0lY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}