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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '434349c112199c50f4541d73f24ce2476eea60c44fea7298e221bfabc2c21399' 
  AND token = 'UewkzED2VZMC1PbrLH8pHUw+A6oyKjxtlSJ9JocxoiM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}