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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b17799ebe43686cd3f8ec2f2da369a002eb7f1fad2354af1364a7cdc2d4009a' 
  AND token = 'pI1qLLco5SaIBgywhlLNvLDoYC1zOfuY95Ql5rgrDyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}