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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ace22e7023965e3accb9f049aa23e0df9eedd3031d11c00b353d0893b8e4eb' 
  AND token = 'ty21G48t9lWK8+eLlJ4+aXOhBSFn4fNDw+9Owet3CDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}