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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec972ccfafdd68040da5ef3aa82da196febfff97eb4dba8cdfb061f4232c0101' 
  AND token = 'b1Q7d3DWb7HLa6ECjwxlYvs+VgW3kcI7gxaVaJ2Ywdk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}