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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe2b298c1b3da74e112abaee84591372fcaf885c9ac9507c6f3a395ed522a726' 
  AND token = 'fCK+pANR8dTzP4yOM4rXXt8pfrF6UvEd07MxZMmYFQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}