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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15a78ffd36b536a78ee1c6ab824a4c8ee67064dc7dfbe64cad8f8c5924dab21f' 
  AND token = 'n//yWumDJRmEp79gEh4n7Gs0apQj38zyV5F+WWXs5YI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}