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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b19b04f97e1a2410267beca144f98c8f6001c1ee659b160d6048f25ecb7e44c' 
  AND token = 'pBEf9nA4JH362qLFcOQse5ZIF3eUSa5RQSXrJ4sylVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}