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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '304980d62caea5830c2f8c14fa654b41c98b64084a2180620bbfa4d3ee6ba0fd' 
  AND token = 'zMPtv2oGlKnL1FstgZ3XIweS30seLRWC65HYC7lXAgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}