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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f0d7d1635145b5bfc9c632e35505d2d66d1757fef7e1caf0322439c7c40677d' 
  AND token = 'UoQCU1bO6QRcxESe7pK2eQnxRs3OE37m/vL/dv5Ng1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}