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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e49bfee2b397de48633447cf9187b54e7cd36e0d7a734bb7a694fe570b3c0c9b' 
  AND token = 'rVPhdGvxzBCng847SIHgWC+P9DRlCWtdGDlPg/QDL00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}