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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59335d5bc8d8ee8abc99a4e756f56cea0a64bd44ec0914e29c376fe858823065' 
  AND token = '4uz2aOrluNa4C7junTjepnCX595x5EVIbFZR3f7DYGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}