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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a56174ef384df2bf1f2114c81c245eced1621a9e83288a7bfb25055fca27921' 
  AND token = '0d+Lo3nxoF6PdrIcwEg5llA8+tBisDAzsQmQGOwGayU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}