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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a854eaa32738494038f157f6ed0a6a11f571188e851be33e7217048664853f4e' 
  AND token = 'tsEFYr8xiFXzmadKziiKGBp751m/1K+z6s7hG3LUJnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}