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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726e258e965e1e71fb6fa656f84351a3c580daf8f32648d6a1b0f1b5779bfc90' 
  AND token = 'o3GQiYPhT1pyFTNDEJmT/7OVVdyow0xas9xA6slKStc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}