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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca01f2f03c5f9c4c4749353064cb584410d59c78bffa44720d1fa42000d22bc9' 
  AND token = 'y4Hxn33CRhxrRFjOqZczX6UI0sgBE9D3LDksSbQmV7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}