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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58177b2739c593ee87b6842fae8f96f152a63f5bbc2a51a98db776aeed6584ad' 
  AND token = 'QccdeDefuy4IPIL1cQ5nhbghbrImSx9huHuVfjdgLQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}