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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae7ecf6f8025304b322120b41947fa06f3b18fb0543a981bb25fc48c13f40a3' 
  AND token = '4m3zICajR4J64YlqLiRp4x9Dee5Z0ydVRRtPz1qHiWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}