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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5224f750ab1b6cfefdb116e665e35f2711a1730056f714a178d8a06edc2a1c78' 
  AND token = 'w9xXQlu+0Ykokl8wmHk81PK3KgU7J8FqKBoKseegf3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}