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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6206f4c8ce7b58669689f5ca022533d82bb18418f54eb2a6f99aa3cf1564b3' 
  AND token = 'C8oLOtD0Zk+92fnqxtV6DohD1n+nbTK7jPUrAuj5oHU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}